Cholestasis syndrome

Cholestasis syndrome, also known as cholestasis, refers to the impairment of bile production or flow caused by various intrahepatic and extrahepatic factors, preventing the normal flow of bile to the duodenum. This leads to the accumulation of substances that should be excreted in bile (such as conjugated bilirubin, bile acids, cholesterol, and alkaline phosphatase) in the blood, resulting in a series of clinical manifestations. The main symptoms include pruritus, steatorrhea due to malabsorption of fat-soluble nutrients, osteoporosis, and xanthomas.