Kaposiform hemangioendothelioma

Kaposiform hemangioendothelioma (KHE) is a rare, locally aggressive vascular tumor of endothelial origin that predominantly affects infants and children. It is characterized by diffuse, invasive proliferation of blood and lymphatic vessels. Based on tumor morphology, KHE can be classified into superficial type (confined to the skin and subcutaneous soft tissue, without invasion of muscle, bone, chest, or abdominal cavity), mixed type, and deep type. The mixed type is the most common.