Congenital eyelid coloboma

Congenital eyelid coloboma refers to the absence of a portion of the upper or lower eyelid. It can occur unilaterally or bilaterally and is often accompanied by deformities of the canthus, lacrimal system, eyebrow, and orbital bone defects. It is a rare congenital eye disease, mostly sporadic, with familial cases being uncommon. The main symptoms include eyelid defects, absence of eyebrows, ankyloblepharon, corneal dermoid, corneal opacity, strabismus, deformities of the tarsus, eyelashes, lacrimal system, and eyebrows, as well as bony defects of the orbital rim, frontal bone, and maxilla. In some cases, it is a manifestation of facial cleft.