Oral and maxillofacial fibrosarcoma

Oral and maxillofacial fibrosarcoma is a malignant tumor originating from fibroblasts in the oral and facial regions. It can arise from the periosteum of the jawbone, periodontal membrane, and connective tissues within the oral soft tissues, such as the lips, cheeks, and tongue. Occasionally, it also occurs within the jawbone, most commonly in the mandibular symphysis, angle of the mandible, and condylar process. It can also occur in the posterior maxilla and maxillary sinus. Fibrosarcoma within the jawbone is more common in children and young adults, while fibrosarcoma of the oral soft tissues is more common in middle-aged and elderly individuals. Its malignancy depends on the degree of cell differentiation and growth rate.