Disseminated intravascular coagulation

Disseminated intravascular coagulation (DIC) is a clinical syndrome characterized by bleeding and microcirculatory failure. It occurs when various underlying diseases damage the microvascular system, leading to coagulation activation, widespread microvascular thrombosis, massive consumption of coagulation factors, and secondary hyperfibrinolysis (excessive fibrinolysis). DIC is not an independent disease but an intermediate stage in the complex pathological processes of numerous diseases.