Liver failure

Liver failure refers to a syndrome caused by extensive necrosis of hepatocytes due to various reasons, leading to a decrease in the liver's biosynthesis, transformation (detoxification), metabolism, and excretion functions. It is ultimately characterized by coagulation dysfunction, jaundice, hepatic encephalopathy, and hepatorenal syndrome. Liver failure can be divided into four types based on the acuteness and chronicity of the disease course: acute liver failure, subacute liver failure, acute-on-chronic liver failure, and chronic liver failure. The main symptom of liver failure is a general decline in health, with significant systemic fatigue. Gastrointestinal symptoms are particularly prominent, and special clinical symptoms may also appear.