Public condition directory

Disease Database

Browse public condition summaries from China medical resources by stable specialty category.

2553 conditionsPage 210 of 284

Internal MedicineHematology

Hemophagocytic lymphohistiocytosis

Hemophagocytic syndrome (HPS), also known as hemophagocytic lymphohistiocytosis (HLH), is a hyperinflammatory response syndrome caused by genetic or acquired immune dysregulation. Based on the etiology, HPS can be divided into two main categories: Primary (familial) hemophagocytic syndrome (FHPS): More common in neonates. It is a genetic disorder, and patients often carry HPS-related gene defects, diagnosed by genetic testing. Secondary (reactive) hemophagocytic syndrome (SHPS): More common in adults, but can also occur in children. It is often associated with underlying diseases such as infections, tumors, or rheumatic conditions, which trigger immune system activation, ultimately leading to a series of reactive diseases. If currently known HPS-related genes are not detected, but the primary disease is also unclear, it is also classified as secondary HPS. The main symptoms include persistent fever, hepatosplenomegaly, pancytopenia, and the presence of hemophagocytosis in bone marrow, liver, spleen, and lymph node tissues.

View details

Internal MedicineHematology

Leukocytosis

Leukocytes, commonly known as white blood cells, are a type of blood cell found in the blood. They play a role in fighting off pathogens and purifying the blood, making them an important cellular component of blood. An increase in leukocytes can be seen as a self-protective response of the body. Leukocytosis is actually an abnormal condition that patients or their families cannot or can hardly detect, and it is often discovered only during a routine blood test. There are many reasons for an elevated white blood cell count. Leukocytosis can occur due to physiological reasons such as strenuous exercise, emotional fluctuations, late pregnancy in women, after a full meal, and in extreme heat or cold environments. In addition, various diseases such as infections (e.g., common cold, pneumonia, enteritis) and hematological disorders can also lead to an elevated white blood cell count. The most common causes are infection and abnormal bone marrow hematopoietic function.

Disease Database

Hemophagocytic lymphohistiocytosis

Leukocytosis

Hemophilia

Coagulopathy

Myeloproliferative neoplasms

Hematologic diseases

Acute lymphoblastic leukemia

Leukopenia

Myelodysplastic Syndromes