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2553 conditionsPage 207 of 284

Internal MedicineHematology

Hereditary elliptocytosis

Hereditary elliptocytosis is a heterogeneous, familial hemolytic disorder characterized by the presence of a large number of elliptical or oval mature red blood cells in the peripheral blood. It is mostly inherited in an autosomal dominant manner, with a few cases caused by gene mutations. The clinical types of this disease include the latent type (asymptomatic type), hemolytic compensated type, and hemolytic anemic type, with varying degrees of severity. The vast majority of patients may remain asymptomatic throughout their lives, or develop mild to moderate anemia in adulthood that is stable and controllable. A very small number of severe patients may develop jaundice and chronic anemia at a very young age, and some fetuses may even be stillborn.

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Internal MedicineHematology

Hereditary spherocytosis

Hereditary spherocytosis (HS) is a familial genetic disorder caused by a congenital defect in the red blood cell membrane, leading to the formation of spherical red blood cells that are easily destroyed, resulting in hemolysis. There are currently no precise statistics on the incidence of this disease. In northern regions, HS is the most common hereditary hemolytic anemia. The main symptoms include anemia, jaundice of the skin and sclera, and splenomegaly. Cholelithiasis is common, and clinical manifestations vary significantly among different patients.

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Disease Database

Hereditary elliptocytosis

Hereditary spherocytosis

Primary fibrinolysis

Langerhans cell histiocytosis

Sickle cell disease

Acute promyelocytic leukemia

Acute leukemia in children

Acute myeloid leukemia

Autoimmune hemolytic anemia